Genetics Firm Gets Baby-Predicting Patent

THE SCIENTIST: The patent awarded to California-based genetic testing company 23andMe for its “Family Traits Inheritance Calculator” sounded to some bioethicists a lot like a green light for making designer babies based on the genetic profiles of couples seeking to procreate. And for good reason. The patent application, filed by 23andMe more than five years ago, basically lays out a blueprint for how prospective parents could use the company’s technology to choose which gametes to use in an in vitro fertilization scenario to get just the baby they wanted. A child’s eye color, lactose tolerance, and earwax consistency are just few of the traits that 23andMe’s calculator can predict, according to the patent.

“What 23andMe is claiming is a method by which prospective donors of ova and/or sperm may be selected so as to increase the likelihood of producing a human baby with characteristics desired by the prospective parents, the selection being based on a computerized comparison of the genotypic data of the egg provider with that of the sperm provider,” wrote Sigrid Sterckx, a bioethicist at Ghent University in Belgium, and a trio of coauthors in an opinion piece published yesterday (October 3) in Genetics in Medicine. “We cannot elaborate here on this debate, but it is clear that selecting children in ways such as those patented by 23andMe is hugely ethically controversial,” the authors continued. “The use of preimplantation genetic diagnosis to avoid implantation of embryos bearing serious genetic abnormalities is by now becoming commonplace, but a computerized process for selecting gamete donors to achieve a baby with a ‘phenotype of interest’ that the prospective parent ‘desires in his/her hypothetical offspring,’ as 23andMe puts it, seems to have much broader implications, for this process also entails the selection of traits that are not disease related.”

But before Sterckx and her colleagues’s piece was even published, New Scientist was already putting the criticism to 23andMe and asking for the company’s reaction to concerns about the patent. In response to questions posed by New Scientist reporters, 23andMe posted a blog on its website downplaying the possibility that customers could use its inheritance calculator to plan for their ideal baby. “At the time 23andMe filed the patent, there was consideration that the technology could have potential applications for fertility clinics so language specific to the fertility treatment process was included in the patent,” the company wrote. “But much has evolved in that time, including 23andMe’s strategic focus. The company never pursued the concepts discussed in the patent beyond our Family Traits Inheritance Calculator, nor do we have any plans to do so.” … (more)

EDITOR: You can read more about it in Al Gore’s ”The Future”.

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